Thermo Fisher Scientific TrkC Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1-0.5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human TrkC (167-182aa DIRWMQLWQEQGEAKL). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TrkC,uniProtId:Q16288-1,ncbiNodeId:9606,antigenRange:167-182,antigenLength:839,antigenImageFileName:PA5-79766_TrkC_Q16288-1_Rabbit.svg,antigenImageFileNamePDP:PA5-79766_TrkC_Q16288-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.05mg sodium azide, 0.05mg thimerosal

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2746881

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.