Thermo Fisher Scientific Insulin Monoclonal Antibody (D4B8)

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

1-10 µg/mL

-

ELISA (ELISA)

1-10 µg/mL

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

D4B8

Immunogen

Purified human Insulin.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_1076192

Product Specific Information

MA1-10516 detects Insulin from human, bovine, and porcine samples.

MA1-10516 has been successfully used in ELISA and immunohistochemistry (frozen) applications.

The MA1-10516 immunogen is purified human Insulin.

Target Information

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.