Thermo Fisher Scientific Insulin Monoclonal Antibody (D4B8)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA1-10516 detects Insulin from human, bovine, and porcine samples.
It has been successfully used in ELISA and immunohistochemistry (frozen) applications.
The immunogen used is purified human Insulin.

Target Information

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It promotes glycogen storage, triglyceride formation, and synthesis of proteins and nucleic acids.

Insulin is a 51-amino acid polypeptide produced from a precursor peptide, proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) linked by two disulfide bonds and one molecule of C-peptide.

Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. It is also present in tumors of β-cell origin such as insulinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.