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Thermo Fisher Scientific XPF Monoclonal Antibody (UMAB20), UltraMAB
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Thermo Fisher Scientific XPF Monoclonal Antibody (UMAB20), UltraMAB

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XPF 단백질을 표적으로 하는 UMAB20 클론 단일클론 항체로, Western blot, IHC, ICC/IF, ChIP 등 다양한 응용에 적합. 인간, 마우스, 랫, 개 반응성. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 용이.

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UM500020CF
판매단위
pk
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마지막 업데이트 2025. 08. 02. 오전 02:48
Thermo Fisher Scientific UM500020CF XPF Monoclonal Antibody (UMAB20), UltraMAB 100 ug pk판매 단위 pk ·
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883,700원VAT 포함 972,070원

Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (UMAB20), UltraMAB

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:500
Immunocytochemistry (ICC/IF) 1:100
ChIP assay (ChIP) Assay-Dependent
Peptide Array (Array) Assay-Dependent

Product Specifications

Specification Description
Species Reactivity Dog, Human, Mouse, Rat
Host/Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone UMAB20
Immunogen Full-length human recombinant XPF protein produced in HEK293 cells
Conjugate Unconjugated
Form Lyophilized
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 8% trehalose
Contains No preservative
Storage Conditions -20°C, avoid freeze/thaw cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The ERCC1/XPF endonuclease complex is involved in DNA repair mechanisms, including:

  • Nucleotide excision repair (NER) for UV-induced and bulky chemical lesions
  • Recombination repair of interstrand cross-links

In mammalian cells:

  • XPG cleaves 3′ of the DNA lesion
  • ERCC1/XPF complex makes the 5′ incision
    This complex likely processes recombination intermediates during DNA repair.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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