Thermo Fisher Scientific SF3B5 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SF3B5 protein. Validated for immunoprecipitation. Suitable for research use in studying pre-mRNA splicing mechanisms. Supplied as liquid, 1 mg/mL, stored at 4°C. Predicted cross-reactivity with mouse and bov...
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Applications
Immunoprecipitation (IP)
- Tested Dilution: 8–15 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 36 to 86 of human Splicing factor 3B subunit 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Predicted reactivity by homology: Mouse, Bovine
Target Information
SF3B5 is a protein-coding gene involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome.
The SF3B complex is required for the formation of the spliceosomal A complex by enabling stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.
Sequence-independent binding of the SF3A/SF3B complex upstream of the branch site is essential and may anchor U2 snRNP to the pre-mRNA.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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