Thermo Fisher Scientific SF3B5 Polyclonal Antibody
SF3B5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 20 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 1 to 50 of human Splicing factor 3B subunit 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted reactivity by homology: Bovine.
Target Information
SF3B5 is a protein-coding gene involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, which is part of the spliceosome. The SF3B complex is required for the assembly of the spliceosomal A complex, formed by stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence-independent binding of the SF3A/SF3B complex upstream of the branch site is essential, potentially anchoring U2 snRNP to the pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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