Thermo Fisher Scientific DUSP12 Polyclonal Antibody
Human DUSP12 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB 및 IP에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 순도 제공. 액상 형태로 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 20 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 1 to 50 of human Dual specificity protein phosphatase 12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Dual specificity phosphatases (DUSPs) deactivate target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. DUSPs are divided into six subgroups based on sequence similarity (PRLs, Cdc14 phosphatases, PTENs, myotubularins, MKPs, atypical DUSPs).
DUSP inhibitors may modulate MAPK and cellular responses. Expression and activity of DUSP family members control MAPK intensity and duration, influencing physiological responses.
DUSP12 (YVH1, GKAP) contains a DUSP catalytic domain and an extended C-terminal domain possibly related to glucokinase regulation. It is localized in both cytoplasm and nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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