Thermo Fisher Scientific SF3B5 Polyclonal Antibody
Rabbit polyclonal antibody against human SF3B5 for WB and IP applications. Targets residues 1–50 of SF3B5. Supplied as liquid, 1 mg/mL, stored at 4°C. Predicted cross-reactivity with bovine. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution / Usage |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 20 µL/mg of lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residues 1–50 of human Splicing factor 3B subunit 5 (SF3B5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Predicted reactivity by homology: Bovine.
Target Information
SF3B5 is a protein-coding gene involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. The SF3B complex is required for the formation of the A complex, which involves stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence-independent binding of the SF3A/SF3B complex upstream of the branch site is essential and may anchor U2 snRNP to pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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