Thermo Fisher Scientific ESRP2 Polyclonal Antibody
Human ESRP2 단백질(aa107–322)에 특이적인 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제, 1 mg/mL 액상 형태. A431, HepG2 양성 대조 추천. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- View 2 publications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 107–322 of Human ESRP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549616 |
Product Specific Information
- Recommended positive controls: A431, HepG2
- Predicted reactivity: Mouse (93%), Rat (92%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RBM35A, also known as ESRP2, is an mRNA splicing factor that, together with ESRP1, coordinates an epithelial cell-type-specific splicing program. These proteins regulate posttranscriptional expression of genes such as FGFR2, CD44, CTNND1, and ENAH, influencing protein translation via 5′ UTRs. Loss of ESRP-regulated splicing induces epithelial-mesenchymal transition–related morphological changes.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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