Thermo Fisher Scientific AgRP Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:2,000

-

Immunohistochemistry (Frozen) (IHC (F))

1:1,000-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Sheep, Rat

Published species

Mouse

Host/Isotype

Guinea pig / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a region (82-131) within the carboxy domain of mouse agouti related protein conjugated to carrier protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AgRP,uniProtId:P56473-1,ncbiNodeId:10090,antigenRange:82-131,antigenLength:131,antigenImageFileName:PA1-18414_AgRP_P56473-1_Guinea_pig.svg,antigenImageFileNamePDP:PA1-18414_AgRP_P56473-1_Guinea_pig_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10981693

Product Specific Information

Reconstitute in 50 µL sterile water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8 °C. It is recommended that a thawed sample is stored at 4 °C for no longer than 2 weeks. Allocation of appropriate anti-bacterial agent can increase shelf life by several weeks. Diluted serum should be prepared as required. Long term stability requires storage, preferably in small aliquots at -20 °C or lower. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this.

Target Information

Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.