Thermo Fisher Scientific Ghrelin Polyclonal Antibody
Ghrelin 및 Obestatin 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 인간, 마우스, 랫트 반응성. PBS/BSA 버퍼에 보관, -20°C에서 안정적 저장.
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- PA11070
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues F(1) N A P F D V G I K L S G A Q Y Q Q H G R A L(23) of the rat Obestatin gene. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074594 |
Product Specific Information
PA1-1070 detects Obestatin in mouse and rat samples. This product does not detect endogenous levels of the hormone in rat stomach.
PA1-1070 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~2.5 kDa protein representing synthetic Obestatin.
The PA1-1070 immunogen is a synthetic peptide corresponding to residues F(1) N A P F D V G I K L S G A Q Y Q Q H G R A L(23) of the rat Obestatin gene. This sequence is conserved in mouse and differs by only one amino acid in human. This peptide (Cat. # PEP-290) is available for neutralization and control experiments.
Target Information
GHRL encodes the ghrelin-obestatin preproprotein, which generates ghrelin and obestatin.
- Ghrelin: Ligand for the growth hormone secretagogue receptor type 1; regulates growth hormone release, stimulates appetite, adiposity, and gastric acid secretion.
- Obestatin: Potential ligand for the orphan G protein-coupled receptor GPR39; involved in satiety and may reduce food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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