Thermo Fisher Scientific PERP Polyclonal Antibody
PERP 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 생쥐 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, p53 관련 세포사멸 연구에 활용됩니다. 고순도 Affinity Chromatography 정제 및 1 mg/mL 농도로 제공됩니다.
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Thermo Fisher Scientific PERP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PERP (Accession Q96FX8), corresponding to amino acid residues Q37–I87 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900373 |
Product Specific Information
This antibody detects endogenous levels of total PERP.
Target Information
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several molecules involved in the p53 network—such as Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP, and PERP—have been identified and cloned.
PERP (also known as PIGPC1 and THW) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates its gene, resulting in PERP-mediated apoptosis.
The expression of PERP induces cell death and serves as a mediator of p53-induced apoptosis. PERP shares sequence similarity with PMP-22/gas3 and is a member of the PMP-22/gas3 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-115738_PERP_Q96FX8-1_Rabbit.svg
- PA5-115738_PERP_Q96FX8-1_Rabbit_PDP.jpeg
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