Thermo Fisher Scientific PEX3 Polyclonal Antibody
PEX3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제 및 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PEX3 (Accession P56589), corresponding to amino acid residues R11–N61 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900375 |
Product Specific Information
Antibody detects endogenous levels of total PEX3.
Target Information
Peroxin 3 (PEX3), also known as peroxisomal biogenesis factor 3 or TRG18, is a 373 amino acid multi-pass membrane protein localized to peroxisomes. It belongs to the Peroxin family and is expressed ubiquitously. PEX3 interacts with Peroxin 19 and plays a crucial role in peroxisome biosynthesis, membrane vesicle assembly, and maintenance of peroxisomal integrity. It acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Mutations in PEX3 cause peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both resulting from defective peroxisomal protein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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