Thermo Fisher Scientific Pericentrin Polyclonal Antibody
Pericentrin 단백질을 검출하기 위한 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, -20°C 보관.
- 카탈로그번호
- PA5115736
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PCNT (Accession O95613), corresponding to amino acid residues L3269–G3319 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900371 |
Product Specific Information
Antibody detects endogenous levels of total Pericentrin – Centrosome Marker.
Target Information
This gene encodes a protein identified in a screen for genes expressed in metastatic cells, specifically mammary adenocarcinoma cell lines. Expression of this gene correlates with metastatic potential in certain carcinomas, though it is also expressed in normal tissues. Its role in metastasis remains unclear. Initially thought to be part of the NuRD complex, it is more likely a distinct but similar protein sharing DNA-binding, dimerization, and methylation-related domains. This gene product likely regulates transcription through chromatin remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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