Thermo Fisher Scientific Phospho-PRPS1 (Ser180) Polyclonal Antibody
PRPS1 단백질의 Ser180 인산화 부위를 특이적으로 인식하는 폴리클로날 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 인간, 생쥐, 랫드 시료에 반응합니다. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRPS1 (Accession P60891), corresponding to amino acid residues around phosphorylated Ser180. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817628 |
Product Specific Information
Antibody detects endogenous levels of PRPS1 only when phosphorylated at S180.
Target Information
This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis.
Defects in this gene are associated with phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5, and Arts Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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