Thermo Fisher Scientific ABHD4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000
• Publications: [참조 없음]

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200
• Publications: [참조 없음]

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.

Target Information

The α/β hydrolase superfamily includes diverse enzymes involved in key biochemical processes and disease mechanisms. Despite varied sequences and substrates, members share a canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad of histidine, acid, and nucleophile.
These enzymes are targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.

• ABHD1: Metabolizes smoking xenobiotics
• ABHD2: Involved in atherosclerosis development
• ABHD4: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE), participates in biosynthesis of N-acyl ethanolamines
• ABHD5: Mutations contribute to Chanarin-Dorfman syndrome
• ABHD6: May play a role in nervous system metabolism and signaling
• ABHD14A: Possibly involved in granule neuron development

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.