
Thermo Fisher Scientific ABHD4 Polyclonal Antibody
ABHD4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 최적화되어 있습니다. 고순도(>95%) 항원 친화 크로마토그래피 정제 제품이며, 인간·생쥐·랫트 반응성을 갖습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [참조 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [참조 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human ABHD4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719595 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The α/β hydrolase superfamily includes diverse enzymes involved in key biochemical processes and disease mechanisms. Despite varied sequences and substrates, members share a canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad of histidine, acid, and nucleophile.
These enzymes are targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.
- ABHD1: Metabolizes smoking xenobiotics
- ABHD2: Involved in atherosclerosis development
- ABHD4: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE), participates in biosynthesis of N-acyl ethanolamines
- ABHD5: Mutations contribute to Chanarin-Dorfman syndrome
- ABHD6: May play a role in nervous system metabolism and signaling
- ABHD14A: Possibly involved in granule neuron development
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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