
Thermo Fisher Scientific B4GALT2 Polyclonal Antibody
B4GALT2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간, 마우스, 랫트 시료에서 반응. 항원 친화 크로마토그래피로 정제되었으며, 고순도와 안정성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human B4GALT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719601 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum by epitope-specific immunogen affinity chromatography. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
B4GALT2 is a type II membrane-bound glycoprotein that specifically utilizes UDP-galactose as a donor substrate. It transfers galactose in a β1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl. Each β4GalT enzyme participates in the biosynthesis of distinct glycoconjugates and saccharide structures.
These proteins possess an N-terminal hydrophobic signal sequence that directs them to the Golgi apparatus, where it remains as a transmembrane anchor.
Based on sequence similarity, β4GalTs are grouped as follows:
- β4GalT1 and β4GalT2
- β4GalT3 and β4GalT4
- β4GalT5 and β4GalT6
- β4GalT7
The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is modulated by α-lactalbumin, though it is not expressed in lactating mammary tissue.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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