Thermo Fisher Scientific PLOD2 Polyclonal Antibody
PLOD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 0.8 mg/mL 농도, PBS/glycerol buffer 보존. 연구용 전용 제품.
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Thermo Fisher Scientific PLOD2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 260–380 of human PLOD2/LH2 (NP_0009262) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855592 |
Product Specific Information
Immunogen sequence:
ILLNYFGNYV PNSWTQDNGC TLCEFDTVDL SAVDVHPNVS IGVFIEQPTP FLPRFLDILL TLDYPKEALK LFIHNKEVYH EKDIKVFFDK AKHEIKTIKI VGPEENLSQA EARNMGMDFC R
Target Information
The PLOD2 gene encodes a membrane-bound homodimeric enzyme localized to the cisternae of the rough endoplasmic reticulum. This enzyme, requiring iron and ascorbate as cofactors, catalyzes the hydroxylation of lysyl residues in collagen-like peptides. Hydroxylysyl groups formed serve as carbohydrate attachment sites, crucial for collagen crosslink stability.
Deficiencies in lysyl hydroxylase activity are linked to Ehlers-Danlos syndrome type VIB, and mutations in this gene are associated with Bruck syndrome. Alternative splicing generates multiple transcript variants encoding different isoforms.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-110181_PLOD2_O00469-1_Rabbit.svg, PA5-110181_PLOD2_O00469-1_Rabbit_PDP.jpeg)
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