Thermo Fisher Scientific CD100 Polyclonal Antibody
Human CD100(SEMA4D) 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer(0.02% sodium azide) 용액 형태로 제공. 2–8°C 보관, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA14201
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues G(147) K N E D G K G R C P F(158) of human CD100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months; for long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2185713 |
Product Specific Information
PA1-4201 detects CD100 in human samples.
This antibody has been successfully used in Western blot applications.
By Western blot, it detects a ~158 kDa protein representing CD100 in transfected CHO cells.
The immunogen is a synthetic peptide corresponding to residues G(147) K N E D G K G R C P F(158) of human CD100.
Target Information
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development.
CD100 (also known as semaphorin 4D), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and enhances their viability in vitro.
CD100 modifies CD40–CD40L B cell signaling by promoting B cell aggregation and survival while downregulating CD23 expression.
CD72 acts as a lymphocyte receptor for the class IV semaphorin CD100, regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells, weakly expressed on NK cells, EBV-transformed B cells, monocytes, and tumor/peripheral blood T cell lines, and more strongly on activated T and B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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