Thermo Fisher Scientific NFATC2 Polyclonal Antibody
Rabbit polyclonal antibody for detection of human NFATc2 (NFAT1/NFATp); validated for Western blot; antigen affinity purified; supplied as liquid in PBS with sodium azide; suitable for immunological research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues A(269) S P Q R S R S P S P Q P(281) of human NFATc2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560295 |
Product Specific Information
- PA1-4198 detects NFAT2 in human samples.
- NFATc2 is also known as NFAT1 or NFATp.
- PA1-4198 has been successfully used in Western blot procedures.
- The immunogen is a synthetic peptide corresponding to residues A(269) S P Q R S R S P S P Q P(281) of human NFATc2.
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of proteins that collectively regulate the immune response. Four NFAT proteins—NFAT1 (NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3)—are encoded on separate genes and expressed as several splice variants. These proteins share limited sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein, NFAT5, differs from isoforms 1–4 in lacking many Fos/Jun contact sites and its localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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