Thermo Fisher Scientific NF-H Monoclonal Antibody (RNF 404)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

Immunohistochemistry (Frozen) (IHC (F))

1:50-1:100

-

Product Specifications

Species Reactivity

Bovine, Dog, Chicken, Guinea pig, Human, Mouse, Non-human primate, Sheep, Rabbit, Rat, Xenopus

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

RNF 404

Immunogen

Neurofilament preparation of calf brain tissue

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

purified

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_325536

Product Specific Information

OMA1-06115 specifically detects the phosphorylated 200 kDa neurofilament from Human, Bovine, Canine, Chicken, Guinea Pig, Non-human primate, mouse, Rabbit, Rat, Ovine and Xenopus tissues.

OMA1-06115 has been successfully used in Western blot, IHC (F), and IHC (P) procedures. By Western blot, this antibody detects an ~200 kDa protein representing the phosphorylated form of the 200 kDa neurofilament from human brain homogenate.

OMA1-06115 antigen is cytoskeletal preparation of calf brain tissue.

Target Information

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.