Thermo Fisher Scientific PODXL Monoclonal Antibody (OTI9C2), TrueMAB
인간 PODXL 단백질을 인식하는 Mouse IgG1 단클론 항체로 IHC(P) 실험에 적합. Lyophilized 형태로 제공되며 1 mg/mL 농도, PBS 기반 버퍼 포함. 연구용으로만 사용 가능하며 재구성 및 결합 실험에 용이.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–461 of human PODXL produced in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein is a key component of glomerular podocytes—highly differentiated epithelial cells with interdigitating foot processes covering the glomerular basement membrane.
Other biological functions include:
- Binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements
- Role in hematopoietic cell differentiation
- Expression in vascular endothelium cells and binding to L-selectin
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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