Thermo Fisher Scientific BAMBI Monoclonal Antibody (OTI5D5), TrueMAB
인간 BAMBI 단백질(aa 21-152)을 항원으로 제작된 Mouse IgG1 단클론 항체. Western blot에 적합하며, 비결합형·동결건조 형태로 제공. 재구성 후 1 mg/mL 농도 유지. TGF-beta 신호 조절 및 암 연구에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21–152 of human BAMBI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane-spanning glycoprotein acting as a negative regulator of TGF-beta signaling during development.
Its transcription is influenced by beta-catenin, BMP, Smad3, and Smad4.
BAMBI expression increases in colorectal and hepatocellular carcinomas compared to non-cancerous tissues and is highly expressed during odontogenesis.
It is coexpressed with BMP-4 during early Xenopus embryogenesis and detectable in poorly metastatic human melanoma cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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