Thermo Fisher Scientific NR2E3 Monoclonal Antibody (OTI4H7), TrueMAB
인간 NR2E3 단백질을 인식하는 마우스 단클론 항체로, Western Blot에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C 보관이 필요합니다. NR2E3 관련 시각세포 발달 연구에 활용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H7 |
| Immunogen | Full length human recombinant protein of human NR2E3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It plays a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, deletion of NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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