Thermo Fisher Scientific TIGIT Chimeric Recombinant Rabbit Monoclonal Antibody (1B4)
마우스 TIGIT에 특이적인 재조합 래빗 단일클론 항체. Western blot, ELISA, Flow cytometry 등 다양한 응용 가능. Protein A로 정제된 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용 가능.
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Applications 및 권장 희석 배수
| Application | Tested Dilution | 참고 문헌 |
|---|---|---|
| Western Blot (WB) | 0.3 µg/mL | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA | 5,000 ng/mL | - |
| Inhibition Assays (IA) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1B4 |
| Immunogen | This antibody was raised by immunising TIGIT-/- mice with recombinant murine TIGIT tetramers. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074642 |
Product Specific Information
Specificity: This antibody is specific for murine TIGIT.
Target Information
Binds with high affinity to the poliovirus receptor (PVR), causing increased secretion of IL10 and decreased secretion of IL12B. Suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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