Thermo Fisher Scientific IL-9 Chimeric Recombinant Rabbit Monoclonal Antibody (D9302C12)
마우스 IL-9에 특이적인 키메릭 재조합 토끼 단클론 항체입니다. Flow Cytometry 및 Inhibition Assay에 사용 가능합니다. HEK293 세포에서 발현되었으며, Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C에서 보관 권장.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Inhibition Assays (IA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | D9302C12 |
| Immunogen | This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074644 |
Product Specific Information
Specificity: This antibody is specific for murine IL-9.
Target Information
Interleukin 9 (IL-9) is produced by activated T helper 2 (Th2) lymphocytes. IL-9 regulates many cell types involved in classical Th2-associated asthma responses, including B and T lymphocytes, mast cells, eosinophils, and epithelial cells.
The mouse IL-9 cDNA encodes a 144 amino acid precursor protein with an 18 amino acid signal peptide that is cleaved to form the mature cysteine-rich protein with a molecular mass of 14 kDa. Native mouse IL-9 is heavily glycosylated.
TGF beta has been reported to play an important role in the differentiation of IL-17-producing T helper cells and inducible regulatory T cells by reprogramming Th2 cells to secrete IL-9, thereby driving the differentiation of Th9 cells directly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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