Thermo Fisher Scientific CD18 Monoclonal Antibody (CLB-LFA-1/1), FITC
인간 CD18에 특이적인 마우스 단클론 항체로 FITC 형광 표지되어 있으며, 유세포분석에 적합합니다. 높은 형광 효율과 수용성, 안정적인 PBS/BSA 보관용액 구성으로 신뢰성 있는 세포 표면 분석에 활용됩니다.
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Applications
- Flow Cytometry (Flow): Assay-dependent
Publications
- Miscellaneous PubMed (Misc): 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CLB-LFA-1/1 |
| Immunogen | Human CD18 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10373688 |
Product Specific Information
FITC conjugates provide high absorptivity, excellent fluorescence quantum yield, and good water solubility, making them suitable for cell surface staining and flow cytometry applications.
Target Information
CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leukocytes. It forms heterodimers with CD11 molecules (CD11a–d), constituting β2 integrins such as LFA-1, Mac-1, CR3, and others. These integrins are essential for leukocyte adhesion, migration, and signaling. Deficiency or mutation of CD18 leads to leukocyte adhesion deficiency type I (LAD1) and related immune disorders. CD18 also serves as a receptor for Mannheimia haemolytica leukotoxin.
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