Thermo Fisher Scientific AQP0 Polyclonal Antibody
AQP0 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 인간 및 영장류 시료에 반응하며, 동결건조 상태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- OSA00102W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:3,000 | – |
| Immunohistochemistry (IHC) | 1:2,000–1:3,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human AQP0 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: AQP0.
Target Information
AQP0 is the most abundant endogenous protein in the plasma membrane of lens fiber cells. It functions as both a water pore and a structural component involved in fiber-fiber adhesion, essential for lens organization.
AQP0 possesses a unique pore constriction responsible for gating, holding only three water molecules that are too far apart to form hydrogen bonds.
The C-terminal domain undergoes extensive post-translational modifications, including truncations during lens aging due to m-calpain and other proteolytic or non-enzymatic mechanisms. These modifications may contribute to cataract formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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