Thermo Fisher Scientific ALDH3A1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ALDH3A1. Validated for WB and IHC applications. Lyophilized form with no preservative. Recommended storage at 4°C short term or -20°C long term. Suitable for research use only.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human ALDH3A1 conjugated to a blue carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: ALDH3A1.
Target Information
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. It is highly expressed in the stomach and more strongly in the cornea, representing between 5–50% of the water-soluble protein fraction in mammalian corneas. Aldh3A1 is thought to protect the cornea from UV-induced oxidative stress through detoxification of reactive aldehydes and direct absorption of UV energy. Mice lacking both Aldh3A1 and Aldh1A1 show increased cataract formation following UVB exposure, indicating potential compensatory roles between these enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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