Thermo Fisher Scientific Nogo Receptor Recombinant Rabbit Monoclonal Antibody (M5)
인간, 마우스, 랫트 Nogo Receptor(NgR1)에 반응하는 재조합 토끼 단클론 항체입니다. Western blot, Flow cytometry, ELISA, IP 등에 사용 가능합니다. HEK293 세포 발현, Protein A 정제, 1 mg/mL 농도, 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | M5 |
| Immunogen | (His)₆-tagged fragment of rat NgR1 (amino acids 278–473) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074379 |
Product Specific Information
- Specificity: The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding).
Target Information
NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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