Thermo Fisher Scientific Cyclin G1 Polyclonal Antibody
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Cyclin G1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 마우스, 랫트 반응성. 고순도(>95%) 항체로 세포주기 조절 연구에 활용. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View publication |
| Immunohistochemistry (IHC) | – | View publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 180–220 of human Cyclin G1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553345 |
Product Specific Information
- Detects endogenous Cyclin G1 protein at a molecular weight of 29 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Cyclins are regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks), which play key roles in controlling cell cycle progression.
- Cdc2–cyclin B complex: controls G2 to M transition
- Cdc2–cyclin A complex: regulates S phase progression
- G1 cyclins: control G1 to S transition
Cyclin G contains an N-terminal cyclin box and a C-terminal domain homologous to the tyrosine phosphorylation site of the EGF receptor. Cyclin G expression is induced within 3 hours of growth stimulation and remains elevated without cell cycle dependency. Cyclin G2 shares 53% amino acid sequence identity with Cyclin G1, with peak expression in late S phase, whereas Cyclin G1 expression is constitutive.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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