Thermo Fisher Scientific Bcl-W Monoclonal Antibody (F.584.7)
Bcl-W 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 최적화되어 있습니다. 사람, 마우스, 랫트에 반응하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 제품으로 연구용에 적합합니다.
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Applications
- Western Blot (WB): 1:1,000
- View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F.584.7 |
| Immunogen | Synthetic peptide corresponding to residues surrounding alanine 39 of Bcl-w |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 107 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10983656 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRα gene on chromosome 14.
Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues.
An alternative splicing event in exon 4 results in two transcripts:
- Bcl-w: encodes a protein of 193 amino acids
- Bcl-w/rox: encodes a protein 333 amino acids in length
The rox portion of Bcl-w/rox shows about 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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