Thermo Fisher Scientific Carbonic Anhydrase VA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 39-305 of human CA5A (NP_0017301) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carbonic Anhydrase VA,uniProtId:P35218-1,ncbiNodeId:9606,antigenRange:39-305,antigenLength:305,antigenImageFileName:PA5-89996_Carbonic_Anhydrase_VA_P35218-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89996_Carbonic_Anhydrase_VA_P35218-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.05 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805883

Product Specific Information

Immunogen sequence: CAWQTSNNTL HPLWTVPVSV PGGTRQSPIN IQWRDSVYDP QLKPLRVSYE AASCLYIWNT GYLFQVEFDD ATEASGISGG PLENHYRLKQ FHFHWGAVNE GGSEHTVDGH AYPAELHLVH WNSVKYQNYK EAVVGENGLA VIGVFLKLGA HHQTLQRLVD ILPEIKHKDA RAAMRPFDPS TLLPTCWDYW TYAGSLTTPP LTESVTWIIQ KEPVEVAPSQ LSAFRTLLFS ALGEEEKMMV NNYRPLQPLM NRKVWASFQA TNEGTRS; Positive Samples: K-562, LO2, HepG2; Cellular Location: Mitochondrion

Target Information

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA5A gene encodes for the CA V protein which is expressed in the mitochondrial matrix in liver tissues, but can also be detected in many other tissues. In ureagenesis, the CA V protein may be involved in providing bicarbonate to carbamoyl phosphate synthetase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.