Thermo Fisher Scientific MIB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human MIB2(Accession Q96AX9), corresponding to amino acid residues F693-P743. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MIB2,uniProtId:Q96AX9-1,ncbiNodeId:9606,antigenRange:693-743,antigenLength:955,antigenImageFileName:PA5-100871_MIB2_Q96AX9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100871_MIB2_Q96AX9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2850368

Product Specific Information

Antibody detects endogenous levels of total MIB2.

Target Information

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.