Thermo Fisher Scientific QRFPR Polyclonal Antibody
QRFPR 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. 액상 형태, -20°C 보관. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human QRFPR (Accession Q96P65), corresponding to amino acid residues T277–C327 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854516 |
Product Specific Information
Antibody detects endogenous levels of total GPR103.
Target Information
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit extracellular signals (ligand binding) into intracellular signals (G protein activation).
GPR signaling is an evolutionarily ancient mechanism used by eukaryotes to sense environmental stimuli and mediate cell-cell communication.
All GPRs have seven membrane-spanning domains, and their extracellular parts can be glycosylated. These loops contain two conserved cysteine residues forming disulfide bonds to stabilize receptor structure.
GPR103 is a 455-amino-acid protein highly expressed in the brain, retina, trigeminal ganglion, hypothalamus, and vestibular nucleus. In peripheral tissues, expression occurs in the heart, kidney, and testis.
GPR103 may regulate adrenal function, and the hypothalamic neuropeptide 26RFa acts as its endogenous ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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