Thermo Fisher Scientific HRH3 Polyclonal Antibody
HRH3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, Affinity Chromatography로 정제되었습니다. -20°C에서 보관하며, 뇌 신경전달물질 조절 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HRH3 (Accession Q9Y5N1), corresponding to amino acid residues V153–S203 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854509 |
Product Specific Information
Antibody detects endogenous levels of total HRH3.
Target Information
H3 Histamine Receptor regulates the release of neurotransmitters such as norepinephrine and somatostatin.
In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons (central and peripheral nervous systems), it acts as a presynaptic heteroreceptor.
Multiple isoforms of H3 receptors are produced by alternative splicing.
Histamine H3 receptor is primarily expressed in the brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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