Thermo Fisher Scientific BAK Polyclonal Antibody
BAK 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며 -20°C에서 안정적.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BAK1 (Accession Q16611), corresponding to amino acid residues M1–E33 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854519 |
Product Specific Information
Antibody detects endogenous levels of total Bak.
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. Members of this family form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities. This protein localizes to mitochondria and induces apoptosis by interacting with and accelerating the opening of the mitochondrial voltage-dependent anion channel, leading to loss of membrane potential and cytochrome c release. It also interacts with tumor suppressor P53 after exposure to cell stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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