Thermo Fisher Scientific AVPR1B Polyclonal Antibody
Rabbit polyclonal antibody targeting human AVPR1B, suitable for WB and ICC/IF. Detects endogenous AVPR1B protein. High purity via affinity chromatography, supplied as liquid form in PBS with glycerol. For research use only.
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Thermo Fisher Scientific AVPR1B Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human AVPR1B (Accession P47901), amino acids T283–C333 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854518 |
Product Specific Information
Antibody detects endogenous levels of total AVPR1B.
Target Information
Vasopressin V1B receptor is expressed in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, characterized by seven membrane-spanning helices. They exist in active and inactive forms, with ligand binding inducing conformational changes that trigger G-protein signaling and downstream effects.
Studies of GPCR regulation and deactivation have significant implications for cellular physiology and drug development. Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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