Thermo Fisher Scientific AVPR1B Polyclonal Antibody

Thermo Fisher Scientific AVPR1B Polyclonal Antibody

Applications and Tested Dilutions

• Western Blot (WB): 1:500–1:1,000
• Immunocytochemistry (ICC/IF): 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total AVPR1B.

Target Information

Vasopressin V1B receptor is expressed in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, characterized by seven membrane-spanning helices. They exist in active and inactive forms, with ligand binding inducing conformational changes that trigger G-protein signaling and downstream effects.
Studies of GPCR regulation and deactivation have significant implications for cellular physiology and drug development. Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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