Thermo Fisher Scientific SIN3A Recombinant Rabbit Monoclonal Antibody (10G3)
SIN3A 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. HEK293 발현 시스템에서 생산, 고순도 친화 크로마토그래피 정제. 인체 반응성, 비결합형 액상 형태로 연구용에 적합.
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Thermo Fisher Scientific SIN3A Recombinant Rabbit Monoclonal Antibody (10G3)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10G3 |
| Immunogen | Synthesized peptide derived from human mSin3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092618 |
Target Information
Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein, involved in transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B.
Both contain four paired amphipathic helix (PAH) domains and directly interact with several transcriptional repressors, including HDAC1, HDAC2, RbAp46, MeCP2, Mad/Max heterodimer, SMRT, and N-CoR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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