Thermo Fisher Scientific KappaB ras1 Polyclonal Antibody
KappaB ras1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제. PBS 버퍼에 0.02% sodium azide 포함, 2–8°C 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (IHC) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide from near the center of human KappaB ras 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157444 |
Product Specific Information
- Suggested positive control: 293 cell lysate
- PA5-20340 can be used with blocking peptide PEP-0460
Target Information
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are small proteins similar to Ras-like small GTPases that associate with Ikappa-B, an inhibitor of the transcription factor NF-kappa-B.
Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta. Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain.
Inactive Ikappa-B-alpha–NF-kappa-B complexes can shuttle between the nucleus and cytoplasm, while Ikappa-B-beta–NF-kappa-B complexes remain in the cytoplasm.
KappaB-ras proteins preferentially bind to Ikappa-B-beta through this unique ankyrin region, modulating its cellular localization and degradation rate.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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