Thermo Fisher Scientific KappaB ras2 Polyclonal Antibody
KappaB ras2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. NF-kappa-B 활성 조절 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the carboxy terminus of human KappaB ras2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152313 |
Product Specific Information
- A suggested positive control is RAW264.7 cell lysate.
- PA5-20342 can be used with blocking peptide PEP-0462.
Target Information
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation.
May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit.
It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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