Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), eFluor 450, eBioscience
마우스 Ly-6G(Gr-1) 항원을 인식하는 단클론 항체로, eFluor 450 형광체가 결합되어 있습니다. Flow cytometry에 최적화되어 있으며, 중성구 표지 및 분석에 유용합니다. 405 nm excitation/445 nm emission 특성을 가지며, 연구용으로 사용됩니다.
- 카탈로그번호
- 48-9668-8x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), eFluor 450, eBioscience
Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), eFluor 450, eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 3 publications |
| Flow Cytometry (Flow) | 0.5 µg/test | View 31 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), eFluor™ 450, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A8-Ly6g |
| Conjugate | eFluor™ 450 |
| Excitation / Emission Max | 405 / 445 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2637123 |
Additional Available Formats
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395 / 563 / 661 / 737
- Brilliant Violet 421 / 480 / 650 / 786
- FITC
- Functional Grade
- PE / PE-Cyanine5 / PE-Cyanine7 / PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436 / 600 / 702
- Custom conjugation available
Product Specific Information
The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G (Gr-1), a 25-kDa GPI protein expressed exclusively by neutrophils. It plays an important role in neutrophil infiltration, recruitment, and migration, associating with B2 integrins CD11a and CD11b.
Unlike RB6-8C5, this antibody binds specifically to Ly-6G on neutrophils and has been used for neutrophil depletion with reported antagonist activity.
Applications Reported: Flow cytometric analysis.
Applications Tested: Tested on mouse bone marrow cells, ≤0.5 µg per test (100 µL volume, 10⁵–10⁸ cells/test). Antibody titration recommended for optimal performance.
Fluorochrome Information:
eFluor™ 450 is an alternative to Pacific Blue™, excited at 405 nm and emits at 445 nm. Ensure instrument compatibility.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
Ly6G (Lymphocyte antigen 6 complex locus G6D)
Component of the myeloid differentiation antigen Gr-1, together with Ly6C. Expressed by myeloid-derived cells in bone marrow (21–25 kDa). Marker for peripheral neutrophils, monocytes, and granulocytes.
Expression correlates with granulocyte differentiation and maturation. Involved in anti-tumor response; Ly6G ligation may inhibit local immune responses.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.