Thermo Fisher Scientific AKT3 Monoclonal Antibody (9A5.H9.G7), APC

Applications and Tested Dilution

Product Specifications

Additional Formats

• Unconjugated
• Biotin
• FITC
• PE
• Custom conjugation available

Product Specific Information

• Store vial at 4°C prior to restoration.
• Restore with deionized water (or equivalent).
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• Centrifuge if not clear after standing at room temperature.
• For extended storage, aliquot and freeze at -20°C or below.
• Avoid freeze/thaw cycles.
• Store reagent in the dark and use subdued lighting during handling and incubation.

Anti-AKT3 antibody is directed against human AKT3 and detects both unphosphorylated and phosphorylated forms. Cross-reactivity with AKT3 from mouse and rat is expected due to 100% sequence identity of the immunogen. Cross-reactivity with AKT2 and AKT1 has not been determined.

Target Information

AKT3 (PKB gamma) is stimulated by PDGF, insulin, and IGF1. It participates in biological processes such as:

• Cell proliferation and differentiation
• Apoptosis and tumorigenesis
• Glycogen synthesis and glucose uptake

Alternatively spliced transcript variants encoding distinct isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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