Thermo Fisher Scientific CD8 alpha Monoclonal Antibody (EP72), Biotin
Chicken CD8α 인식을 위한 Mouse 모노클론 항체로, Biotin 결합 형식 제공. Flow Cytometry에 적합하며 고순도 정제된 액상 형태. PBS 기반 안정화 버퍼 포함, 4°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | EP72 |
| Immunogen | Chicken splenocytes |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4, with proprietary stabilizer |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C |
| RRID | AB_2745754 |
Additional Formats
Target Information
Cluster of differentiation 8 (CD8) is a type I transmembrane glycoprotein of the immunoglobulin receptor family, playing an integral role in T cell signal transduction, differentiation, and activation.
CD8 is mainly expressed on T cells as a disulfide-linked heterodimer of CD8α and CD8β, functioning as a co-receptor with T cell receptor (TCR) for MHC class I molecules.
It is also found as a homodimer of CD8α on subsets of T cells, NK cells, monocytes, and dendritic cells.
Binding of MHC-I/peptide complexes triggers Lck kinase recruitment, leading to lymphokine production, motility, and cytotoxic T lymphocyte (CTL) activation.
Activated CTLs are essential for pathogen and tumor cell clearance. Differentiation of naive CD8+ T cells into CTLs is enhanced by IL-2, IL-12, and TGF-β1.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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