Thermo Fisher Scientific RAD52 Polyclonal Antibody
RAD52 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간, 마우스, 랫트에서 반응하며 IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용 DNA 복구 메커니즘 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 80–120 of Human RAD52 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718933 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. These breaks are repaired via homologous recombination (HR) or non-homologous end joining (NHEJ).
Homologous recombination requires the activity of the RAD52 epistasis group, which includes RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2.
RAD52 catalyzes strand annealing reactions and forms oligomers that attach to ends of single-stranded DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-75205_RAD52_P43351-1_Rabbit.svg, PA5-75205_RAD52_P43351-1_Rabbit_PDP.jpeg)
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