Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 사용 가능. Human hnRNP D의 46-98번 아미노산 서열 기반 합성 펩타이드로 면역화. 고순도 (>95%) 항원 친화 크로마토그래피 정제. PBS/glycerol buffer에 보관, 연구용 전용.
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Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 46–98 of Human hnRNP D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718928 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The hnRNP D gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins bind nucleic acids and complex with heterogeneous nuclear RNA (hnRNA). hnRNPs are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. hnRNP D contains two quasi-RRM domains that bind RNAs and localizes to both nucleus and cytoplasm. It plays a role in regulating mRNA stability. Alternative splicing produces four transcript variants.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-75200_hnRNP_D_Q14103-1_Rabbit.svg, PA5-75200_hnRNP_D_Q14103-1_Rabbit_PDP.jpeg)
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