Thermo Fisher Scientific EHMT1 Monoclonal Antibody (1B7B4)
EHMT1 단백질을 표적으로 하는 Thermo Fisher Scientific의 마우스 단클론 항체. Western blot과 ELISA에 적합하며 인간 시료에서 반응. 비결합형 액상 형태로 제공되며 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B7B4 |
| Immunogen | Purified recombinant fragment of GLP expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11009500 |
Product Specific Information
MA5-15277 targets GLP in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of GLP expressed in E. coli.
Target Information
EHMT1 (also known as EUHMTASE1) is a histone methyltransferase that methylates Lys-9 of histone H3 in vitro.
H3 Lys-9 methylation acts as an epigenetic marker for transcriptional repression by recruiting HP1 proteins to methylated histones.
EHMT1 is likely targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and/or DP1.
During the G0 phase, it contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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