Thermo Fisher Scientific Neurogranin Polyclonal Antibody
Neurogranin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용 전용 제품.
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Thermo Fisher Scientific Neurogranin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Neurogranin (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902038 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns; exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated sequences. It is suggested that NRGN is a direct target for thyroid hormone in the human brain, and that regulation of its expression may underlie many effects of hypothyroidism on mental states during development and in adults.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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