Thermo Fisher Scientific Neurogranin Polyclonal Antibody
Neurogranin 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody입니다. Western blot, IHC(P), IHC(F) 등 다양한 응용에 적합합니다. Human, mouse, rat 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:250 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human Neurogranin recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.16 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902039 |
Product Specific Information
Centrifuge briefly prior to opening.
Target Information
Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. Exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated sequences.
It is suggested that NRGN is a direct target for thyroid hormone in the human brain, and that control of expression of this gene could underlie many of the consequences of hypothyroidism on mental states during development and adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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