Thermo Fisher Scientific IL1R2 Monoclonal Antibody (34141)
IL1R2 단일클론 항체로 인간 IL-1 RII를 특이적으로 인식합니다. Western blot, ELISA, 중화 실험에 사용 가능하며, 단백질 A/G 정제 및 무보존제 PBS 버퍼에 동결건조 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| ELISA (Detection) | 0.1–0.4 µg/mL |
| ELISA (Capture) | 2–8 µg/mL |
| Neutralization (Neu) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 34141 |
| Immunogen | Sf 21-derived recombinant human IL-1 RII (Phe14–Glu343, Ser56Gly and Glu297Gly) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609079 |
Available Conjugated Formats
Product Specific Information
- When used with biotinylated human IL-1 RII affinity purified polyclonal detection antibody in sandwich ELISAs, no significant cross-reactivity or interference was observed with recombinant human IL-1ra, IL-1 RI, recombinant mouse IL-1ra, or recombinant rat IL-1ra.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
The IL1R2 protein is a cytokine receptor belonging to the interleukin-1 receptor family. It binds IL1A, IL1B, and IL1R1/IL1RA, acting as a decoy receptor that inhibits ligand activity. IL4 can antagonize IL1 by inducing IL1R2 expression and release. This gene is part of a cytokine receptor cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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