Thermo Fisher Scientific MCT2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to the C-terminal residues S(465) N A Q S V T S E R E T N I(478) of human MCT2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MCT2,uniProtId:O60669-1,ncbiNodeId:9606,antigenRange:465-478,antigenLength:478,antigenImageFileName:PA1-25304_MCT2_O60669-1_Goat.svg,antigenImageFileNamePDP:PA1-25304_MCT2_O60669-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

TBS with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2285857

Product Specific Information

PA1-25304 detects MCT2 from human samples.

Target Information

Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.